(Pituitary Tumor; Nervous System Tumor)
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- A family or personal history of multiple endocrine neoplasia, type 1 (MEN1)—a hereditary condition that increases the risk of developing pituitary, hypothalamus, and parathyroid and pancreatic tumors
- Other inherited disorders such as Carney complex or acromegaly (giantism)
- Blurred vision or tunnel vision
- Milk production in nonlactating women
- Loss of or irregular periods
- Lack of interest in sex
- Vaginal dryness
- Swelling of the neck
- Rapid heartbeat
- Weight loss
- Menstrual disturbance
- Skin changes—increased facial hair, acne, bruising, or bluish stretch marks
- Buffalo hump—increased fatty tissue in back
- Obesity, especially around the wrist
- Round face
- Enlarged hands and feet
- Excessive growth and height
- Oily skin
- Excess sweating
- Blood tests
- Urine tests
- Dopamine agonists—cabergoline, bromocriptine
- Octreotide or long-acting versions
- Conventional therapy—radiation is directed at the pituitary from a source outside the body
- Stereotactic radiosurgery—an intense radiation beam is targeted directly at the tumor
- Proton beam radiotherapy—a beam of protons (positively charged particles) is directly focused on the tumor
American Cancer Society http://www.cancer.org
Hormone Health Network http://www.hormone.org
Canadian Cancer Society http://www.cancer.ca
Brain Tumor Foundation of Canada http://www.braintumour.ca
Becker A, Daly AF: The clinical, pathological, and genetic features of familial isolated pituitary adenomas. Eur J Endocrinol 2007;57:371-82.
Beshay VE, Beshay JE, Halvorson LM: Pituitary tumors: diagnosis, management, and implications for reproduction. Semin Reprod Med 2007;25:388-401.
Detailed guide: pituitary tumor. American Cancer Society website. Available at: http://www.cancer.org/docroot/CRI/CRI%5F2%5F3x.asp?rnav=cridg&dt=61. Accessed February 27, 2014.
Pituitary tumors information page. National Institute of Neurological Disorders and Stroke website. Available at: http://www.ninds.nih.gov/disorders/pituitary%5Ftumors/pituitary%5Ftumors.htm. Updated February 14, 2014. Accessed February 27, 2014.
Pituitary tumors (PDQ): treatment. National Cancer Institute website. Available at: http://www.cancer.gov/cancertopics/pdq/treatment/pituitary/patient. Updated January 3, 2014. Accessed February 27, 2014.
- Reviewer: Kim Carmichael, MD
- Review Date: 03/2014 -
- Update Date: 04/29/2014 -